New shot could shield against malaria for months

NCT ID NCT06408857

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new drug called MAM01 to see if it is safe and could help prevent malaria for at least 4 months. It involved 125 healthy adults and children living in parts of Africa where malaria is common. Researchers gave different doses of MAM01 or a placebo and monitored for side effects and how the drug behaves in the body.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MAM01

What this could lead to

If successful, MAM01 could provide a new way to prevent malaria for several months, reducing infections in areas where malaria is common.

What could go wrong

This is an early Phase 1 trial focused on safety and dosing, so it is too soon to know if MAM01 will actually prevent malaria. The results may not apply to all populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Plasmodium falciparum malaria malaria prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IDRC-Infectious Disease Research Collaboration, IDRC Tororo Hospital Station Road

    Tororo, 749, Uganda

  • JCRC-Joint Clinical Research Centre

    Kampala, 10005, Uganda