New antibody shot shows promise against malaria in early trial

NCT ID NCT05891236

First seen Jun 14, 2026 · Last updated Jun 23, 2026 · Updated 3 times

Summary

This early-stage trial tested a lab-made antibody called MAM01 in 63 healthy adults who had never had malaria. The goal was to see if it is safe and can prevent malaria infection when people are deliberately exposed to the parasite. The study is complete, but results are not yet public.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Center for Vaccine Development and Global Health, 685 W. Baltimore Street

    Baltimore, Maryland, 21201, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MAM01 (a lab-made antibody that targets the malaria parasite)

What this could lead to

If successful, this antibody could provide temporary protection against malaria, especially for travelers or in outbreaks.

What could go wrong

This is a very early, small trial (63 people) in healthy adults who have never had malaria. It may not work in real-world settings or provide long-term protection.

Conditions

The condition(s) this trial relates to.

malaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.