Could a Man-Made bone putty replace your own bone in ankle surgery?
NCT ID NCT07225751
First seen Jun 24, 2026 · Last updated Jul 08, 2026 · Updated 4 times
Summary
This study tests a synthetic bone graft called MagnetOs against the standard method of using a patient's own bone for ankle or hindfoot fusion. About 126 adults needing fusion surgery will be randomly assigned to receive either MagnetOs or an autograft. The main goal is to see if the synthetic graft leads to similar bone fusion on CT scans at 24 weeks, potentially offering a less painful option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- MagnetOs (synthetic bone graft putty)
- What this could lead to
- If it works, this could offer a less painful alternative to using a patient's own bone for fusion surgery, avoiding a second surgical site.
- What could go wrong
- This is a relatively small, early-stage study (126 people) comparing to standard care. The synthetic graft may not fuse as reliably as the patient's own bone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centers for Advanced Orthopaedics
RECRUITINGFalls Church, Virginia, 22042, United States
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Hughston Foundation Inc
RECRUITINGColumbus, Georgia, 31909, United States
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Integrity Orthopedics and Sports Medicine
RECRUITINGChattanooga, Tennessee, 37404, United States
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OrthoCarolina Research Institute, Inc
RECRUITINGCharlotte, North Carolina, 28207, United States
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Reconstructive Orthopaedic Associates II dba Rothman Orthopaedic Institute
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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Steadman Philippon Research Institute
RECRUITINGVail, Colorado, 81657, United States
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