Could a Man-Made bone putty replace your own bone in ankle surgery?
NCT ID NCT07225751
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests a synthetic bone graft called MagnetOs against the standard method of using a patient's own bone for ankle or hindfoot fusion. About 126 adults needing fusion surgery will be randomly assigned to receive either MagnetOs or an autograft. The main goal is to see if the synthetic graft leads to similar bone fusion on CT scans at 24 weeks, potentially offering a less painful option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MagnetOs (synthetic bone graft putty)
What this could lead to
If it works, this could offer a less painful alternative to using a patient's own bone for fusion surgery, avoiding a second surgical site.
What could go wrong
This is a relatively small, early-stage study (126 people) comparing to standard care. The synthetic graft may not fuse as reliably as the patient's own bone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Erlanger Orthopaedics
RECRUITINGChattanooga, Tennessee, 37403, United States
Contact
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Hughston Foundation Inc
RECRUITINGColumbus, Georgia, 31909, United States
Contact Email: •••••@•••••
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OrthoCarolina Research Institute, Inc
RECRUITINGCharlotte, North Carolina, 28207, United States
Contact Email: •••••@•••••
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Reconstructive Orthopaedic Associates II dba Rothman Orthopaedic Institute
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Email: •••••@•••••
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Steadman Philippon Research Institute
RECRUITINGVail, Colorado, 81657, United States
Contact Email: •••••@•••••