Could a single dose of magnesium cut Post-Surgery opioid use?

NCT ID NCT07328893

Recruiting now Symptom relief Sponsor: Tata Main Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a single dose of magnesium sulfate given during gallbladder surgery can lower the amount of morphine patients need afterward. 106 adults having laparoscopic gallbladder removal will be randomly assigned to receive either magnesium or a placebo. The goal is to see if magnesium reduces pain and the need for strong painkillers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: magnesium sulfate
What this could lead to: If it works, this could offer a simple, low-cost way to reduce pain and morphine use after gallbladder surgery.
What could go wrong: This is a small, early-phase trial. Magnesium may not reduce pain significantly, and results may not apply to other surgeries or patients.

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Conditions

The condition(s) this trial relates to.

agnosia cholelithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESIA, POSTOPERATIVE

Contacts and locations

Locations

Dr.Deb Sanjay Nag
RECRUITING

Jamshedpur, Jharkhand, 831011, India
Tata Main Hospital
RECRUITING

Jamshedpur, Jharkhand, 831001, India

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