Dissolving screws could spare ankle fracture patients a second surgery

NCT ID NCT07693933

Not yet recruiting Disease control Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This study tests a new type of screw made from a magnesium alloy that slowly dissolves in the body over two to three years. Unlike standard metal screws, these biodegradable screws may not need to be removed in a second surgery. The trial enrolls adults aged 18 to 80 with unstable ankle fractures and follows them for 12 months to measure ankle function, healing, and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: RemeOs magnesium-based biodegradable screw
What this could lead to: If successful, these screws could eliminate the need for a second surgery to remove metal hardware, reducing complications and recovery time.
What could go wrong: This is a small, early study with only 28 participants. The screws may not hold the bone as well as metal, or could cause unexpected reactions as they dissolve.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANKLE FRACTURES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Ankle Fractures ankle injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANKLE FRACTURES SYNDESMOTIC INJURY

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.