Could a Magnesium-Melatonin combo soothe nighttime leg cramps and improve sleep?

NCT ID NCT07651514

Recruiting now Symptom relief Sponsor: StudySetGo Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether a daily supplement containing magnesium and melatonin can improve sleep quality in adults aged 40 to 75 who experience poor sleep due to nighttime leg cramps. Over 8 weeks, participants take either the supplement or a placebo each night and wear an Oura Ring to track sleep. They also complete short questionnaires via a smartphone app, all from home.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Magnesium and melatonin based multi-ingredient dietary supplement
What this could lead to: If it works, this could offer a simple, non-prescription option to improve sleep for people troubled by nighttime leg cramps.
What could go wrong: This is a small, early-stage trial with only 50 participants. The supplement may prove no better than a placebo, and individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Sleep-Wake Transition Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LEG CRAMPS, NOCTURNAL POOR SLEEP QUALITY

Contacts and locations

Locations

StudySetGo Decentralised team
RECRUITING

Palm Beach Gardens, Florida, 33418, United States

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