Could a Magnesium-Melatonin combo soothe nighttime leg cramps and improve sleep?

NCT ID NCT07651514

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether a daily supplement containing magnesium and melatonin can improve sleep quality in adults aged 40 to 75 who experience poor sleep due to nighttime leg cramps. Over 8 weeks, participants take either the supplement or a placebo each night and wear an Oura Ring to track sleep. They also complete short questionnaires via a smartphone app, all from home.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Magnesium and melatonin based multi-ingredient dietary supplement

What this could lead to

If it works, this could offer a simple, non-prescription option to improve sleep for people troubled by nighttime leg cramps.

What could go wrong

This is a small, early-stage trial with only 50 participants. The supplement may prove no better than a placebo, and individual results may vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Sleep-Wake Transition Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • StudySetGo Decentralised team

    RECRUITING

    Palm Beach Gardens, Florida, 33418, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••