Scientists reprogram Patients' own cells to hunt cancer

NCT ID NCT02989064

Summary

This early-stage study tested whether a patient's own immune cells could be genetically modified in a lab to recognize and attack cancer cells, then safely given back to the patient. It involved 10 adults with specific types of bladder, skin (melanoma), or head and neck cancers who had a particular genetic marker. The main goal was to find a safe dose and understand the side effects of this personalized cell therapy.

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Contacts and locations

Locations

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Hospital Universitario 12 Octubre Avda. de Córdoba

    Madrid, 28041, Spain

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G1X6, Canada

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Start Madrid-FJD, Fundación Jimѐnez Díaz

    Madrid, 28040, Spain

  • Tennessee Oncology - Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Vanderbilt - Ingram Cancer Center

    Nashville, Tennessee, 37203, United States

  • Washington University - School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.