Mouth device vs. CPAP: which works best for sleep apnea?

NCT ID NCT07677332

Not yet recruiting Disease control Sponsor: University of Copenhagen Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study compares two common treatments for moderate obstructive sleep apnea: a custom mouth device that moves the jaw forward (MAD) and a machine that blows air through a mask (CPAP). Researchers want to see how well each treatment improves breathing during sleep and reduces daytime sleepiness. The trial includes 70 adults with moderate sleep apnea and will also look at side effects like jaw discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mandibular advancement device (MAD) and continuous positive airway pressure (CPAP)
What this could lead to: If MAD works as well as CPAP for some patients, it could offer a more comfortable, accessible treatment option for moderate sleep apnea.
What could go wrong: This is a relatively small study (70 people) and MAD may be less effective than CPAP overall. Side effects like jaw pain or bite changes are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBSTRUCTIVE SLEEP APNEA (OSA)

Contacts and locations

Locations

University of Copenhagen

Copenhagen, 2200, Denmark

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