Mouth device offers new hope for sleep apnea patients who Can't use CPAP
NCT ID NCT07132307
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a custom mouthpiece (mandibular advancement device) for people with moderate to severe obstructive sleep apnea who cannot tolerate CPAP and have not improved with a nerve stimulation implant. Researchers will measure if the device reduces breathing pauses during sleep. The trial involves 30 adults and uses home sleep tests to check results.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mandibular advancement device (MAD) - ProSomnus Sleep Device
What this could lead to
If it works, this could offer a new treatment option for people with severe sleep apnea who have not been helped by other therapies.
What could go wrong
This is a small, early study with only 30 people. The device may not work for everyone, and results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••