Scientists probe immune clues to save failing dental implants

NCT ID NCT07569432

First seen May 08, 2026 · Last updated Jun 23, 2026 · Updated 8 times

Summary

This study investigates how immune cells called macrophages behave in gum disease around dental implants (peri-implantitis). Researchers will measure various inflammatory markers in tissue samples from 120 participants, including smokers and non-smokers. The goal is to understand why some implants fail and how smoking worsens the condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Biruni University

    RECRUITING

    Istanbul, Turkey (Türkiye)

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward better ways to diagnose or treat peri-implantitis by targeting specific immune cells.

What could go wrong

This is an observational study, not a treatment trial. It is small and early-stage, so findings may not lead to direct clinical changes.

Conditions

The condition(s) this trial relates to.

Peri-Implantitis Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.