Scientists probe immune clues to save failing dental implants

NCT ID NCT07569432

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates how immune cells called macrophages behave in gum disease around dental implants (peri-implantitis). Researchers will measure various inflammatory markers in tissue samples from 120 participants, including smokers and non-smokers. The goal is to understand why some implants fail and how smoking worsens the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could point toward better ways to diagnose or treat peri-implantitis by targeting specific immune cells.
What could go wrong
This is an observational study, not a treatment trial. It is small and early-stage, so findings may not lead to direct clinical changes.

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Conditions

The condition(s) this trial relates to.

Peri-Implantitis Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Biruni University

    RECRUITING

    Istanbul, Turkey (Türkiye)

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