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Blood and wearable data may predict depression swings

NCT ID NCT05910957

Ongoing Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study looks at whether combining information from blood samples and smartwatch data can help diagnose major depression and predict when a person moves between active depression and treated depression. Researchers will track symptoms using standard depression rating scales. The goal is to find objective markers that could improve how depression is detected and managed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a way to diagnose depression using objective data from blood and wearables, and to predict when someone might relapse.
What could go wrong
This is a small pilot study with only 40 participants, so results may not apply to everyone. It is exploratory and not designed to prove a treatment works.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER UNIPOLAR, NON-PSYCHOTIC MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

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