New hope for advanced colorectal cancer: first human trial launches
NCT ID NCT05464030
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study tests a new drug called M9140 in people with advanced colorectal cancer that has not responded to standard treatments. The drug works by targeting a protein on cancer cells to deliver a chemotherapy-like agent directly to the tumor. The trial has two parts: first finding a safe dose, then testing how well it works in a larger group.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for COLORECTAL CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Aichi Cancer Center Hospital
RECRUITINGNagoya, Japan
Contact
-
Asan Medical Center
RECRUITINGSeoul, South Korea
Contact
-
California Cancer Associates for Research & Excellence, Inc.
COMPLETEDEncinitas, California, 92024, United States
-
California Cancer Associates for Research & Excellence, Inc.
COMPLETEDFresno, California, 93720, United States
-
Cancer Institute Hospital of JFCR
RECRUITINGKōtoku, Japan
Contact
-
Centro Integral Oncologico Clara Campal
RECRUITINGMadrid, Spain
Contact
-
Complejo Hospitalario Universitario de Santiago
RECRUITINGSantiago de Compostela, Spain
Contact
-
Hospital Clinic de Barcelona
RECRUITINGBarcelona, Spain
Contact
-
Hospital HM Nou Delfos
RECRUITINGBarcelona, Spain
Contact
-
Hospital Universitari Vall d'Hebron - VHIR
RECRUITINGBarcelona, Spain
Contact Email: •••••@•••••
Contact
-
Hospital Universitario 12 de Octubre
RECRUITINGMadrid, Spain
Contact
-
Hospital Universitario Fundacion Jimenez Diaz
RECRUITINGMadrid, Spain
Contact
-
Hospital Universitario Quironsalud Madrid - NEXT Oncology
RECRUITINGMadrid, Spain
Contact Email: •••••@•••••
Contact
-
Hospital Universitario Reina Sofia
RECRUITINGCórdoba, Spain
Contact
-
Hospital Universitario Virgen del Rocio
RECRUITINGSeville, Spain
Contact
-
Hospital del Mar
RECRUITINGBarcelona, Spain
Contact
-
ICO l'Hospitalet - Hospital Duran i Reynals
RECRUITINGL'Hospitalet de Llobregat, Spain
Contact
-
Kanagawa Cancer Center
RECRUITINGYokohama, Japan
Contact
-
Kindai University Hospital
RECRUITINGOsakasayama-shi, Japan
Contact
-
Kyungpook National University Chilgok Hospital
RECRUITINGDaegu, South Korea
Contact
-
MD Anderson Cancer Center - Oncology
RECRUITINGHouston, Texas, 77030, United States
Contact
-
Mary Crowley Cancer Research
RECRUITINGDallas, Texas, 75230, United States
Contact
-
NEXT Oncology
RECRUITINGSan Antonio, Texas, 78229, United States
Contact
-
National Cancer Center
RECRUITINGGoyang-si, South Korea
Contact
-
National Cancer Center Hospital - Dept of Gastroenterology
RECRUITINGChūōku, Japan
Contact Email: •••••@•••••
Contact
-
National Cancer Center Hospital East
RECRUITINGKashiwa-shi, Japan
Contact
-
Rhode Island Hospital
RECRUITINGProvidence, Rhode Island, 02903, United States
Contact
-
Saitama Cancer Center
RECRUITINGKitaadachi-gun, Japan
Contact
-
Samsung Medical Center
RECRUITINGSeoul, South Korea
Contact
-
Seoul National University Bundang Hospital
RECRUITINGSeongnam, South Korea
Contact
-
Seoul National University Hospital
RECRUITINGSeoul, South Korea
Contact
-
Severance Hospital, Yonsei University Health System
RECRUITINGSeoul, South Korea
Contact
-
Shizuoka Cancer Center
RECRUITINGSunto-gun, Japan
Contact
-
The Ottawa Hospital Cancer Centre
RECRUITINGOttawa, Canada
Contact
-
University Health Network - Princess Margaret Cancer Centre
RECRUITINGToronto, Canada
Contact
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can we predict who will survive a bowel surgery leak?
- Can a Two-Drug attack shrink Hard-to-Treat colorectal tumors?
- Can a new drug ST316 shrink Hard-to-Treat tumors?
- A mobile app aims to turn health awareness into action — a trial puts it to the test
- Can a walking routine alter cancer biomarkers? new trial investigates
- Web tool aims to empower rare cancer patients in genomic choices