Lymph node removal during cancer surgery: helpful or harmful?
NCT ID NCT06262516
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looks at whether removing lymph nodes during standard kidney-ureter surgery helps people with upper tract urothelial carcinoma. About 94 adults with this rare cancer will be randomly assigned to get either the standard surgery alone or the surgery plus lymph node removal. Researchers will track cancer recurrence and survival over two years to see if the extra procedure makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Lymph node dissection (surgical procedure)
- What this could lead to
- If it works, this could show that adding lymph node removal during standard surgery helps prevent cancer from coming back.
- What could go wrong
- This is a small, early-stage trial with only 94 participants, so results may not apply to everyone. The added surgery could also increase complications without clear benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cleveland Clinic Glickman Urological and Kidney Institute
RECRUITINGCleveland, Ohio, 44195, United States
-
Southern Illinois University
RECRUITINGSpringfield, Illinois, 62702, United States
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University Hospitals Cleveland Medical Center, Urology Institute, Case Comprehensive Cancer Center
RECRUITINGCleveland, Ohio, 44106, United States
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University of Florida Health Science Center
RECRUITINGGainesville, Florida, 32209, United States
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