New valve device offers hope for High-Risk heart patients
NCT ID NCT06568003
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new device called LuX-Valve Plus, which is a replacement heart valve delivered through a vein, for people with severe tricuspid regurgitation (a leaky heart valve). The 15 participants have symptoms and are not candidates for surgery. The goal is to see if the device can safely reduce the leak and improve symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LuX-Valve Plus system (a replacement heart valve delivered through a vein)
What this could lead to
If it works, this could offer a less risky treatment option for people with severe tricuspid regurgitation who are too sick for open-heart surgery.
What could go wrong
This is a very small early study with only 15 people, so results may not apply to everyone. The procedure carries serious risks like bleeding, stroke, or need for a pacemaker.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for TRICUSPID REGURGITATION (TR) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
-
Henry Ford Health System
Detroit, Michigan, 48202, United States
-
Montefiore Medical Center
New York, New York, 10467, United States