New shot for eczema shows promise in Mid-Stage trial
NCT ID NCT06718101
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a drug called lutikizumab for people with moderate to severe atopic dermatitis (eczema) that hasn't improved with standard treatments. About 80 participants will receive either the drug or a placebo for 16 weeks, then everyone gets the drug for another 32 weeks. The goal is to see if it reduces skin rash and itching safely.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lutikizumab (ABT-981), a drug given as a shot under the skin
What this could lead to
If it works, this could point toward a new treatment option for people with moderate to severe eczema that hasn't responded to standard creams or pills.
What could go wrong
This is an early Phase 2 trial with only 83 people, so results may not apply to everyone. The drug may not work better than placebo, and side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advanced Clinical Research Institute /ID# 272558
Tampa, Florida, 33607, United States
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Arlington Dermatology /ID# 271735
Rolling Meadows, Illinois, 60008, United States
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Center for Clinical Studies - Clear Lake /ID# 271749
Webster, Texas, 77598, United States
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Chapel Allerton Hospital /ID# 274762
Leeds, West Yorkshire, LS7 4SA, United Kingdom
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Clinical Partners /ID# 271791
Johnston, Rhode Island, 02919, United States
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Clinical Trials Research Institute /ID# 274234
Thousand Oaks, California, 91320, United States
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Complete Dermatology - Sugar Land /ID# 274240
Sugar Land, Texas, 77479, United States
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Dermatology Associates of Tyler /ID# 273684
Tyler, Texas, 75703, United States
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Dermatology Research Associates - Los Angeles /ID# 272945
Los Angeles, California, 90045, United States
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Encore Medical Research - Weston /ID# 272539
Weston, Florida, 33331, United States
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Equity Medical, LLC /ID# 272555
New York, New York, 10023-7340, United States
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Hallym University Kangnam Sacred Heart Hospital /ID# 271785
Seoul, Seoul Teugbyeolsi, 07441, South Korea
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Health Concepts /ID# 271744
Rapid City, South Dakota, 57702, United States
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Integrative Skin Science and Research /ID# 274243
Sacramento, California, 95815, United States
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Konkuk University Medical Center /ID# 271789
Seoul, Seoul Teugbyeolsi, 05030, South Korea
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Korea University Ansan Hospital /ID# 271786
Ansan-si, Gyeonggido, 15355, South Korea
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Kyoto University Hospital /ID# 275237
Kyoto, Kyoto, 606-8507, Japan
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Medical Corporation Kojinkai Sapporo Dermatology Clinic /ID# 273619
Sapporo, Hokkaido, 060-0063, Japan
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Oregon Dermatology & Research Center /ID# 271733
Portland, Oregon, 97210, United States
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Orion Clinical Research /ID# 274236
Austin, Texas, 78759, United States
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Peak Dermatology Aesthetics and Wellness Fountain Hills /ID# 272550
Fountain Hills, Arizona, 85268, United States
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Research Associates of South Florida /ID# 272549
Miami, Florida, 33134, United States
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Royal Liverpool University Hospital /ID# 272584
Liverpool, L7 8XP, United Kingdom
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Royal United Hospital /ID# 274328
Bath, Bath And North East Somerset, BA1 3NG, United Kingdom
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Seoul National University Hospital /ID# 271787
Seoul, Seoul Teugbyeolsi, 03080, South Korea
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Skin Care Research Boca Raton /ID# 272544
Boca Raton, Florida, 33486-2269, United States
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Somnos Clinical Research /ID# 272943
Lincoln, Nebraska, 68510, United States
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Soon Chun Hyang University Hospital Bucheon /ID# 271788
Bucheon-si, Gyeonggido, 14584, South Korea
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Tachikawa Dermatology Clinic /ID# 273620
Tachikawa-shi, Tokyo, 190-0023, Japan
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Western States Clinical Res /ID# 271748
Wheat Ridge, Colorado, 80033-2896, United States