Massive lupus registry launches to unlock secrets of the disease

NCT ID NCT05934149

Recruiting now Knowledge-focused Sponsor: Lupus Research Alliance Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is building a large registry and biorepository of 3,500 adults with systemic lupus erythematosus (SLE), including those with lupus nephritis and neuropsychiatric lupus. Participants will provide clinical data and biospecimens over time, creating a resource for future research to identify genetic drivers, understand disease mechanisms, and link biomarkers to treatment responses. The goal is to accelerate discoveries that could improve diagnosis and care for lupus patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this registry will provide a rich resource for researchers to discover genetic and biological markers, potentially leading to better treatments and personalized care for lupus.
What could go wrong: This is an observational study, not a treatment trial. It will not directly test any new therapy, and its value depends on future research using the collected data and samples.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

central nervous system lupus lupus nephritis systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUPUS NEPHRITIS NEUROPSYCHIATRIC SYSTEMIC LUPUS ERYTHEMATOSUS SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Contacts and locations

Locations

Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
CHU de Québec - Université Laval
RECRUITING

Québec, Quebec, G1R 2J6, Canada
Columbia University Medical Center
NOT_YET_RECRUITING

New York, New York, 10032, United States
Emory University
RECRUITING

Atlanta, Georgia, 30322, United States
Georgetown University
NOT_YET_RECRUITING

Washington D.C., District of Columbia, 20057, United States
McGill University Health Centre
RECRUITING

Montreal, Quebec, H3H 2R9, Canada
Northwell Health
RECRUITING

New York, New York, 11021, United States
SUNY Upstate
RECRUITING

Syracuse, New York, 13210, United States
The Feinstein Institutes for Medical Research
RECRUITING

Manhasset, New York, 11030, United States
The MetroHealth System
RECRUITING

Cleveland, Ohio, 44109, United States
UCLA
NOT_YET_RECRUITING

Los Angeles, California, 90024, United States
UNC Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27599, United States
UT Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
University Health Network/Toronto Western Hospital
RECRUITING

Toronto, Ontario, M5G 2C4, Canada
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35205, United States
University of Alberta Hospital
RECRUITING

Edmonton, Alberta, AB T6G 2X8, Canada
University of Arizona
RECRUITING

Tucson, Arizona, 85714, United States
University of Calgary
RECRUITING

Calgary, Alberta, T2N 1N4, Canada
University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States
University of Manitoba
RECRUITING

Winnipeg, Manitoba, Canada
University of Massachusetts Memorial Health
RECRUITING

Worcester, Massachusetts, 01605, United States
University of Miami
RECRUITING

Miami, Florida, 33146, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
Wallace Rheumatic Studies Center
RECRUITING

Beverly Hills, California, 90210, United States
Washington University
RECRUITING

St Louis, Missouri, 63130, United States

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