Steroid-Free hope: new lupus kidney treatment trial launches

NCT ID NCT04702256

First seen Dec 12, 2025 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tests whether a drug called obinutuzumab, combined with mycophenolate mofetil (MMF), can control lupus-related kidney disease as well as the standard treatment of oral steroids plus MMF, but without the side effects of long-term steroid use. About 196 people with active lupus nephritis will be randomly assigned to one of the two treatment groups. The main goal is to see if the obinutuzumab group achieves complete kidney response at one year while using fewer or no oral steroids.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LUPUS NEPHRITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Internal medicine, Cochin hospital, APHP

    RECRUITING

    Paris, 75014, France

    Contact

Conditions

Explore the condition pages connected to this study.