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Ultrasound may fine-tune fluid balance in dialysis patients — a trial puts it to the test

NCT ID NCT07721636

Diagnosis Sponsor: Alexandria University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study tests whether using lung ultrasound and the VExUS score can improve how doctors assess fluid status and set the ideal dry weight in people on maintenance hemodialysis. Forty adults with end-stage kidney disease will first be managed with standard clinical exams for 12 weeks, then with ultrasound-guided assessments for another 12 weeks. The goal is to see if ultrasound leads to a more accurate dry weight compared to the standard approach.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ultrasound-based volume assessment (POCUS, lung ultrasound, VExUS score)
What this could lead to
If successful, this approach could help dialysis patients achieve a more accurate dry weight, potentially reducing complications from fluid overload or dehydration.
What could go wrong
This is a small, single-center study with only 40 participants. The ultrasound technique may not be widely applicable or may not improve outcomes over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ESRD patients on maintenance HD for more than three months. * In the HD unit at the Medical Research Institute and Faculty of Medicine. Alexandria University. * Age: 25 -65 years old. * The ability to give informed consent. Exclusion Criteria: * Patients with previous echocardiographic evidence of right heart dysfunction, tricuspid valve disease, or IVC thrombosis. * Patients with liver cirrhosis * Lung diseases: interstitial lung diseases, COPD patients. * Obese (BMI≥30)

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dry weight Hemodialysis patient

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Alexandria University Hospitals

    RECRUITING

    Alexandria, Egypt

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