Can a rheumatoid arthritis drug save lung transplants?
NCT ID NCT06033196
First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 30 times
Summary
This study tests whether adding tocilizumab (a drug that reduces inflammation) to standard anti-rejection medicines can prevent chronic lung allograft dysfunction (CLAD) in lung transplant recipients. 350 adults receiving their first lung transplant will be randomly assigned to get either tocilizumab or a placebo for 20 weeks. The goal is to see if this approach reduces the risk of CLAD, the need for a second transplant, or death over 3 years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Barnes Jewish Hospital/ Washington University SOM (Site #: 71191)
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Boston Children's Hospital and Harvard Medical School (Site #: 71001)
WITHDRAWNBoston, Massachusetts, 02215, United States
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Cedars Sinai Medical Center (Site #: 71146)
RECRUITINGBeverly Hills, California, 90211, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic (Site #: 71101)
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Columbia University Medical Center (Site #: 71113)
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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David Geffen School of Medicine at UCLA (Site #: 71123)
RECRUITINGLos Angeles, California, 90095, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Duke University Medical Center (Site #: 71139)
RECRUITINGDurham, North Carolina, 27710, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Emory University (Site #: 71103)
NOT_YET_RECRUITINGAtlanta, Georgia, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Houston Methodist Hospital (Site #: 71120)
WITHDRAWNHouston, Texas, 77030, United States
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Massachusetts General Hospital (Site #: 71107)
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic Rochester (Site #: 71160)
NOT_YET_RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ohio State University Medical Center (Site #: 71196)
NOT_YET_RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Joseph's Hospital and Medical Center (Site #: 71192)
RECRUITINGPhoenix, Arizona, 85013, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Louis Children's Hospital of Washington University (Site #: 71006)
WITHDRAWNSt Louis, Missouri, 63110, United States
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Temple University (Site #: 71197)
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Florida Shands Hospital (Site #: 71131)
NOT_YET_RECRUITINGGainesville, Florida, 32610, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Maryland Medical Center (Site #: 71138)
WITHDRAWNBaltimore, Maryland, 21201, United States
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University of Texas Health Science at San Antonio (Site #: 71198)
NOT_YET_RECRUITINGSan Antonio, Texas, 78229, United States
Contact Email: •••••@•••••
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University of Texas Southwestern (Site #: 71187)
RECRUITINGDallas, Texas, 75390, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Utah Medical Center (Site #: 71126)
RECRUITINGSalt Lake City, Utah, 84132, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vanderbilt University (Site #: 71174)
NOT_YET_RECRUITINGNashville, Tennessee, 37232-0393, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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