Breathing in xenon: a new MRI method to map lung function

NCT ID NCT01280994

Recruiting now Knowledge-focused Sponsor: Bastiaan Driehuys Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a special MRI technique that uses a harmless xenon gas to create detailed images of lung function. Researchers will compare healthy volunteers and people with interstitial lung disease to see if the method can detect problems with air flow, lung structure, and gas exchange. The goal is to develop a safer, more informative way to assess lung health without radiation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hyperpolarized 129Xenon Gas
What this could lead to: If successful, this could lead to a new, non-invasive way to assess lung function and diagnose lung diseases like fibrosis and emphysema more accurately.
What could go wrong: This is an early-phase study focused on developing the imaging technique, not on treating disease. It may not lead to a direct treatment or benefit for participants.

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Conditions

The condition(s) this trial relates to.

interstitial lung disease lung disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTERSTITIAL LUNG DISEASE

Contacts and locations

Locations

Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States

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