New breath test could catch cystic fibrosis lung damage early in young children

NCT ID NCT02342951

Completed Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a non-invasive breathing test called the lung clearance index (LCI) can detect early lung disease in young children with cystic fibrosis. Researchers tested 53 children aged 3 to 6 years and compared the results with CT scans and other lung function tests. The goal was to see if LCI could help doctors start treatment sooner and choose the best therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could provide a simple, non-invasive way to catch lung problems early in young children with cystic fibrosis, allowing for earlier treatment.
What could go wrong: This is a small, completed observational study, not a treatment trial. The test may not prove reliable enough for routine use, and results may not apply to all children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cystic fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CYSTIC FIBROSIS

Contacts and locations

Locations

Hôpital Necker-Enfants Malades

Paris, 75015, France

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