New hope for Tough-to-Treat lung cancer: trial targets genetic weakness

NCT ID NCT06219174

Summary

This study is testing whether adding an older drug called DFMO to the immunotherapy pembrolizumab can help control advanced lung cancer in people whose tumors have a specific genetic change (STK11 mutation). The first part finds the safest dose, and the second part checks if the combination effectively shrinks tumors. It is for adults with advanced lung cancer who have run out of standard treatment options.

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Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.