New hope for Tough-to-Treat lung cancer: testing a powerful drug duo

NCT ID NCT03600701

Summary

This study is testing whether combining two drugs, atezolizumab and cobimetinib, can help control advanced non-small cell lung cancer that has spread or returned and has stopped responding to a common type of immunotherapy. The trial aims to see if this combination can shrink tumors and slow the cancer's progression in about 51 adults who meet specific health criteria. Researchers will also monitor side effects and study how the treatment affects the body.

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Contacts and locations

Locations

  • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

    Lebanon, New Hampshire, 03756, United States

  • Emory Saint Joseph's Hospital

    Atlanta, Georgia, 30342, United States

  • Emory University Hospital Midtown

    Atlanta, Georgia, 30308, United States

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Hayworth Cancer Center

    High Point, North Carolina, 27262, United States

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • NYP/Weill Cornell Medical Center

    New York, New York, 10065, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • UC San Diego Moores Cancer Center

    La Jolla, California, 92093, United States

  • University of Alabama at Birmingham Cancer Center

    Birmingham, Alabama, 35233, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Pittsburgh Cancer Institute (UPCI)

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Virginia Cancer Center

    Charlottesville, Virginia, 22908, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

  • Wake Forest University at Clemmons

    Clemmons, North Carolina, 27012, United States

  • Wayne State University/Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

Conditions

Explore the condition pages connected to this study.