Lung cancer rebiopsy study aims to uncover immunotherapy resistance
NCT ID NCT04300062
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study collects tumor samples from 50 lung cancer patients whose disease has worsened while on immunotherapy. The goal is to analyze the tissue for clues about why the treatment stopped working. No new drug is being tested; instead, researchers hope to better understand resistance mechanisms to guide future therapies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could reveal why some lung cancers stop responding to immunotherapy, pointing toward better treatments in the future.
What could go wrong
This is an observational study, not a treatment trial. It is small (50 participants) and early-stage, so findings may not lead to immediate changes in care.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Service de Pneumologie et Oncologie thoracique, Hôpital Ambroise Paré, APHP
RECRUITINGBoulogne-Billancourt, 92100, France