Lung cancer 'Mini-Tumors' grown in lab could guide personalized therapy

NCT ID NCT03655015

Recruiting now Knowledge-focused Sponsor: The University of Texas Health Science Center at San Antonio Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study collects tumor samples from 150 lung cancer patients to grow miniature versions called organoids in the lab. Researchers will test how these organoids respond to chemotherapy and targeted drugs, and compare that to how the patient's actual tumor responds. They will also look at circulating tumor cells in the blood. The goal is to build a biobank that can help predict which treatments work best for each person.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which lung cancer treatments will work best for each patient, leading to more personalized care.
What could go wrong: This is an early-stage observational study, not a treatment trial. The organoids may not perfectly mimic real patient responses, and results may not change current care for years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG NEOPLASM

Contacts and locations

Locations

UT Health San Antonio, M.D. Anderson Cancer Center
RECRUITING

San Antonio, Texas, 78229, United States

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