New combo therapy tested to keep advanced lung cancer at bay

NCT ID NCT03559049

Summary

This study tested whether adding a pill called rucaparib to an existing immunotherapy (pembrolizumab) could help control stage IV non-squamous lung cancer for longer after initial chemotherapy. It aimed to see if this two-drug maintenance therapy was safe and could delay cancer progression in 25 patients whose cancer had not worsened after first-line treatment. The trial was terminated early and did not complete its planned enrollment.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • The University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.