Scientists test new drug duo to stall tough lung cancer

NCT ID NCT03170206

Summary

This early-stage trial tested the safety and best dose of a two-drug combination for people with advanced lung cancer driven by a specific KRAS gene change. The study involved 34 adults and combined two oral medications, palbociclib and binimetinib, which work together to block different signals that tell cancer cells to grow. The main goals were to find a safe dose and see how well patients tolerated the treatment.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.