Can a breath test spot lung cancer return?

NCT ID NCT06707519

Recruiting now Knowledge-focused Sponsor: St. Joseph's Healthcare Hamilton Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether DNA from blood, sputum, lung fluid, and breath can help find genetic changes in non-small cell lung cancer. Researchers will collect samples from 210 patients before and after surgery, then follow them for 24 months to check for cancer return. The goal is to see if these sample types are practical and reliable for detecting mutations, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show that simple breath or sputum tests help detect lung cancer mutations or recurrence after surgery, potentially reducing the need for invasive biopsies.
What could go wrong: This is a small, early feasibility study, not a treatment trial. It only tests whether collecting and analyzing these samples is practical, not whether they improve patient outcomes. Results may not apply to all lung cancer patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIRCULATING TUMOR DNA LUNG CANCER

Contacts and locations

Locations

St. Joseph's Healthcare Hamilton
RECRUITING

Hamilton, Ontario, L8N 4A6, Canada

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