Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a paste save infected baby teeth without extraction?

NCT ID NCT07773805

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This trial tests two different pastes—calcium hydroxide-iodoform and a modified triple antibiotic—used in a procedure called LSTR to treat severely infected baby molars in children aged 4 to 7. The goal is to see which paste better stops infection, relieves pain, and preserves the tooth over a 12-month follow-up. Children with restorable infected lower second baby molars are randomly assigned to one of the two treatments, and success is measured by clinical signs like mobility, swelling, and pain, as well as X-ray findings.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Calcium hydroxide-iodoform paste or modified triple antibiotic paste, used in the LSTR technique for treating infected baby molars.
What this could lead to
If one paste proves more effective, it could offer a simpler, less invasive way to save infected baby teeth and prevent early tooth loss in children.
What could go wrong
This is a small, early-stage trial, and results may not apply to all cases. There is a risk of allergic reactions or treatment failure, requiring further procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

4 to 7 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pediatric patients aged 4-7 years * Positive parental informed consent * Restorable necrotic mandibular second primary molars with peri-radicular/furcal involvement and/or pathologic root resorption (external or internal one-third to two-thirds of the root) * Presence of chronic apical abscess or sinus tract or furcation radiolucency Exclusion Criteria: * Medically compromised patient * Children with a known allergy to any of the components being utilized * Molars near exfoliation * Molars with severely resorbed roots more than two thirds, indicated for extraction * Molar with insufficient coronal structure disabling proper coronal seal * Presence of a periapical or interradicular radiolucent area which could compromise the permanent tooth bud

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Dental caries are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

dental caries dental pulp necrosis Periapical Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental caries Dental pulp necrosis Periapical diseases Primary teeth

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.