New radiation 'Lattice' method paired with immunotherapy shows promise for tough cancers

NCT ID NCT07058948

Recruiting now Disease control Sponsor: Tianjin Medical University Cancer Institute and Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests a new radiation technique called lattice radiation therapy (LRT) combined with immunotherapy in 30 people with advanced solid tumors that have not responded to standard treatments. LRT delivers high doses of radiation to small spots inside the tumor while keeping the rest of the tumor at a lower dose, aiming to boost the immune system's ability to fight cancer. The study will measure how many patients' tumors shrink and track any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lattice radiation therapy and immunotherapy
What this could lead to: If successful, this combination could offer a new treatment option for people with advanced solid tumors who have run out of standard therapies.
What could go wrong: This is a small, early-phase study with only 30 participants, so results may not apply to everyone. The combination also carries risks of side effects from both radiation and immunotherapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer lung cancer lung neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMMUNE CHECKPOINT INHIBITOR LUNG CANCER RADIOTHERAPY SOLID CANCERS

Contacts and locations

Locations

Beijing Friendship Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100000, China
Hebei Province Cangzhou Hospital of Integrated Traditional and Western Medicine
RECRUITING

Cangzhou, Hebei, 061000, China
Tianjin Medical University Cancer Institute & Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300000, China

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