New pill tested in kids with Hard-to-Treat cancers
NCT ID NCT03899792
Summary
This study is testing a pill called LOXO-292 in children and teenagers with advanced solid or brain tumors that have a specific genetic change called a RET alteration. The goal is to find a safe and effective dose and to see if the medicine can shrink these difficult-to-treat tumors. It is for patients whose cancer has continued to grow despite standard treatments.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Childrens Hospital of Los Angeles
Los Angeles, California, 90027, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229-3039, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Lombardy, 20133, Italy
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Gustave Roussy
Villejuif, 94805, France
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Hiroshima University Hospital
Hiroshima, 734-8551, Japan
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Hokkaido University Hospital
Sapporo, Hokkaido, 060-8648, Japan
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Hospital Universitari Vall d'Hebron
Barcelona, Barcelona [Barcelona], 8035, Spain
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Kyoto University Hospital
Kyoto, 606-8507, Japan
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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National Cancer Center Hospital
Chuo-ku, Tokyo, 104-0045, Japan
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Nemours Children's Health
Orlando, Florida, 32827, United States
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Rigshospitalet
Copenhagen, 2200, Denmark
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Royal Children's Hospital
Melbourne, Victoria, 3052, Australia
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Seattle Children's Hospital Research Foundation
Seattle, Washington, 98105, United States
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Seoul National University Hospital
Seoul, Korea, 03080, South Korea
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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Texas Childrens Hospital
Houston, Texas, 77025, United States
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The Children's Hospital at Westmead
Westmead, New South Wales, 2145, Australia
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The Children's Hospital for Cancer and Blood Disorders
Aurora, Colorado, 80045, United States
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The Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada
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University College Hospital - London
London, Greater London, NW1 2BU, United Kingdom
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University of Minnesota Hospital
Minneapolis, Minnesota, 55455, United States
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University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, 75390-9063, United States
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Universitätsklinikum Heidelberg
Heidelberg, Baden-Wurttemberg, 69115, Germany
Conditions
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