New surgery technique could improve survival in recurrent throat cancer

NCT ID NCT04425265

Recruiting now Disease control Sponsor: Sun Yat-sen University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two surgical techniques for treating nasopharyngeal cancer that has come back after radiation. 500 participants will be randomly assigned to receive either low-temperature plasma ablation or high-frequency electrocautery. The goal is to see which method leads to better survival without the cancer returning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Plasma radiofrequency ablation (low-temperature) and electrocautery block resection (high-frequency) surgical procedures
What this could lead to: If successful, this could provide a better surgical option for patients with recurrent nasopharyngeal carcinoma, potentially improving survival and reducing complications.
What could go wrong: This is a single-center trial with no blinding, and the results may not apply to all patients. The procedures are invasive and carry risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECURRENT NASOPHARYNGEAL CARCINOMA SURGERY

Contacts and locations

Locations

Sun Yat-sen University Cancer Center
RECRUITING

Guangzhou, Guangdong, 510060, China
The Fifth Affiliated Hospital of Sun Yat-sen University
RECRUITING

Zhuhai, Guangdong, 519000, China
The Nanchang Affiliated Hospital, Sun Yat-Sen University (Nanchang First Hospital)
RECRUITING

Nanchang, Jiangxi, China

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