New surgery technique could improve survival in recurrent throat cancer

NCT ID NCT04425265

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two surgical techniques for treating nasopharyngeal cancer that has come back after radiation. 500 participants will be randomly assigned to receive either low-temperature plasma ablation or high-frequency electrocautery. The goal is to see which method leads to better survival without the cancer returning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Plasma radiofrequency ablation (low-temperature) and electrocautery block resection (high-frequency) surgical procedures

What this could lead to

If successful, this could provide a better surgical option for patients with recurrent nasopharyngeal carcinoma, potentially improving survival and reducing complications.

What could go wrong

This is a single-center trial with no blinding, and the results may not apply to all patients. The procedures are invasive and carry risks like bleeding or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Fifth Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Zhuhai, Guangdong, 519000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Nanchang Affiliated Hospital, Sun Yat-Sen University (Nanchang First Hospital)

    RECRUITING

    Nanchang, Jiangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••