Sound waves zapped into brain to fight pain – study complete!

NCT ID NCT05145426

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new way to treat chronic pain without surgery or drugs. Researchers used low-intensity focused ultrasound (sound waves) to temporarily change brain activity in 61 adults with chronic pain. Participants had brain scans and then received mild heat pulses on their skin while the ultrasound was applied. The goal was to see if the sound waves could reduce how much pain people felt. This was an early study to understand how the brain processes pain, not a treatment yet.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fralin Biomedical Research Institute

    Roanoke, Virginia, 24016, United States