New triple therapy shows promise in shrinking head and neck tumors before surgery

NCT ID NCT06494189

First seen Jan 09, 2026 · Last updated May 03, 2026 · Updated 17 times

Summary

This early-phase study tested a combination of low-dose radiation, an immunotherapy drug (tislelizumab), and a targeted therapy (afatinib) given before surgery to people with head and neck cancer. The main goal was to find a safe dose and see how well the treatment shrinks tumors. Only 9 people took part, and the results help guide future research.

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Contacts and locations

Locations

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610000, China

Conditions

Explore the condition pages connected to this study.