Microdose mushroom study for despair fails to launch
NCT ID NCT05227742
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study planned to test very low doses of psilocybin (the active ingredient in magic mushrooms) in adults with moderate to severe demoralization—feelings of hopelessness and meaninglessness often linked to illness or hardship. The goal was to see if these microdoses could improve mood and thinking without causing hallucinations. However, the study was withdrawn before enrolling any participants, so no results are available.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35209, United States