Microdose mushroom study for despair fails to launch
NCT ID NCT05227742
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study planned to test very low doses of psilocybin (the active ingredient in magic mushrooms) in adults with moderate to severe demoralization—feelings of hopelessness and meaninglessness often linked to illness or hardship. The goal was to see if these microdoses could improve mood and thinking without causing hallucinations. However, the study was withdrawn before enrolling any participants, so no results are available.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35209, United States
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