Magic mushroom therapy tested for End-of-Life distress

NCT ID NCT05403086

First seen Dec 16, 2025 · Last updated May 09, 2026 · Updated 22 times

Summary

This study tests whether psilocybin (the active ingredient in magic mushrooms) can help reduce feelings of demoralization in adults with a life expectancy of 2 years or less. About 100 participants will receive either psilocybin or an active control in a triple-blind setup. The goal is to see if this therapy can ease emotional suffering near the end of life.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

    RECRUITING

    Torrance, California, 90502, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Marin Cancer Care

    RECRUITING

    Greenbrae, California, 94904, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sunstone Therapies

    RECRUITING

    Rockville, Maryland, 20850, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of San Francisco

    RECRUITING

    San Francisco, California, 94518, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.