New drug combo shows promise in advanced breast cancer trial

NCT ID NCT01351909

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 27 times

Summary

This early-stage trial tested the safety and best dose of two drugs—cyclophosphamide and veliparib—given together to people with HER2-negative breast cancer that has spread or cannot be removed by surgery. The goal was to find the right dose for future studies and to see if the combination helps shrink tumors. 35 participants took part in this phase I study.

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Contacts and locations

Locations

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York, New York, 10016, United States

  • Montefiore Medical Center - Moses Campus

    The Bronx, New York, 10467, United States

  • Montefiore Medical Center-Einstein Campus

    The Bronx, New York, 10461, United States

  • Montefiore Medical Center-Weiler Hospital

    The Bronx, New York, 10461, United States

  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

    New York, New York, 10032, United States

Conditions

Explore the condition pages connected to this study.