Could a tiny dose of this pill delay prostate surgery?
NCT ID NCT04530552
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 30 times
Summary
This study tests whether a very low dose of apalutamide, a drug that blocks testosterone, can lower PSA levels in men with early-stage prostate cancer who are about to have their prostate removed. About 34 men will take the drug for 3-4 weeks before surgery. If PSA drops enough, it may suggest that low-dose apalutamide could help some men safely delay or avoid surgery or radiation.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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George Washington University Medical Center
Washington D.C., District of Columbia, 20037, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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NCI - Center for Cancer Research
Bethesda, Maryland, 20892, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University of Arizona Cancer Center - Prevention Research Clinic
Tucson, Arizona, 85719, United States
Conditions
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