Less contrast, same clarity? study aims to make heart surgery prep safer
NCT ID NCT05758701
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study investigates whether using a lower dose of iodine contrast dye in CT scans can still produce high-quality images needed to plan a heart valve replacement procedure (TAVR). Normally, 100 ml of contrast is used, but reducing the dose may help avoid kidney injury and save resources. Participants scheduled for TAVR will receive a reduced contrast dose, and the images will be evaluated for diagnostic quality.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Iodinated contrast agent (Omnipaque)
What this could lead to
If successful, this approach could reduce the amount of contrast dye needed for pre-surgery scans, lowering the risk of kidney injury and saving costs.
What could go wrong
The lower contrast dose might not produce images clear enough for safe surgical planning, and the study is limited to a specific patient group.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Maryland Medical Center
RECRUITINGBaltimore, Maryland, 21201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••