New hope for rare brain disease: Long-Term safety data collected

NCT ID NCT01887938

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed 24 people with metachromatic leukodystrophy (MLD), a rare and serious brain disease, who were already receiving an experimental drug called HGT-1110. The main goal was to check for side effects and immune reactions over a long period. Researchers wanted to see if the drug remained safe for continued use.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHR Orleans - Hopital La Source

    Orléans, 45067, France

  • CHU de Nantes

    Nantes, 44093, France

  • Center for Pediatric Clinical Studies (CPCS)

    Tübingen, Baden-Wurttemberg, 72076, Germany

  • Detska Interni Klinika, Lf Mu A Fn Brno

    Brno, 61300, Czechia

  • Hopital Femme Mere Enfant

    Bron, 69 677, France

  • Hopital Gui de Chauliac - CHRU de Montpellier

    Montpellier, 34000, France

  • Hospital de Clinicas de Porto Alegre

    Porto Alegre, 90035-003, Brazil

  • Hôpital de Bicêtre

    Le Kremlin-Bicêtre, Île-de-France Region, 94275, France

  • Kitakyushu Municipal Yahata Hospital

    Fukuoka, 805-8534, Japan

  • Klinikum Oldenburg

    Oldenburg, 26133, Germany

  • Kurashiki Central Hospital

    Okayama Prefecture, 710-8602, Japan

  • Marien-Hospital Wesel gGmbh

    Wesel, 46483, Germany

  • Osaka University Hospital

    Osaka, 565-0871, Japan

  • Rigshospitalet

    Copenhagen, 2100, Denmark

  • The Children's Hospital at Westmead

    Westmead, 2145, Australia

More trials for these conditions

Other studies related to the condition(s) this trial covers.