New lupus drug ianalumab tested for Long-Term safety

NCT ID NCT06133972

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This study is testing the long-term safety of a drug called ianalumab in people with lupus who have already completed a previous study with the same drug. About 550 participants will receive either ianalumab or a placebo monthly or quarterly for up to several years. The main goal is to see if the drug is safe and tolerable over time, with secondary goals looking at how well it controls lupus symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ianalumab (a biologic drug given as a shot under the skin)
What this could lead to: If successful, this could show that ianalumab is a safe long-term treatment option for people with lupus, helping to control the disease over time.
What could go wrong: This is an extension study focused on safety, not on proving the drug works. It only includes people who already tolerated the drug, so results may not apply to everyone with lupus. Side effects are still possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

systemic lupus erythematosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYSTEMIC LUPUS ERYTHEMATOSUS

Contacts and locations

Locations

Accurate Clinical Research
RECRUITING

Lake Charles, Louisiana, 70601, United States
Accurate Clinical Research
RECRUITING

League City, Texas, 77573, United States
Advanced Medical Research
RECRUITING

La Palma, California, 90623, United States
Ahmed Arif Medical Research Center
RECRUITING

Grand Blanc, Michigan, 48439, United States
Clinical Res Of W Florida
RECRUITING

Clearwater, Florida, 33765, United States
Clinical Research of West Florida Inc
RECRUITING

Tampa, Florida, 33603, United States
Epic Medical Research
RECRUITING

Red Oak, Texas, 75154, United States
GNP Research
RECRUITING

Cooper City, Florida, 33024, United States
Henry Ford Health
RECRUITING

Detroit, Michigan, 48202, United States
IRIS Research and Development
RECRUITING

Plantation, Florida, 33324, United States
Millennium Clinical Trials
ACTIVE_NOT_RECRUITING

Westlake Village, California, 91361, United States
Novartis Investigative Site
RECRUITING

La Plata, Buenos Aires, B1900AWT, Argentina
Novartis Investigative Site
RECRUITING

Quilmes, Buenos Aires, 1878, Argentina
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

San Miguel, Buenos Aires, B1663GKT, Argentina
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

San Miguel, Tucumán Province, T4000CBC, Argentina
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Caba, C1015ABO, Argentina
Novartis Investigative Site
RECRUITING

Caba, C1427CCL, Argentina
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

San Miguel de Tucumán, T4000AXL, Argentina
Novartis Investigative Site
RECRUITING

Maroochydore, Queensland, 4558, Australia
Novartis Investigative Site
RECRUITING

Salvador, Estado de Bahia, 40150 150, Brazil
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Belo Horizonte, Minas Gerais, 30150-221, Brazil
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Niterói, Rio de Janeiro, 24020 096, Brazil
Novartis Investigative Site
RECRUITING

Rio de Janeiro, Rio de Janeiro, 22211-230, Brazil
Novartis Investigative Site
RECRUITING

Barretos, São Paulo, 14784 400, Brazil
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

São Paulo, São Paulo, 01244-030, Brazil
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

São Paulo, São Paulo, 04038-002, Brazil
Novartis Investigative Site
RECRUITING

Salvador, 40323-010, Brazil
Novartis Investigative Site
RECRUITING

Plovdiv, 4002, Bulgaria
Novartis Investigative Site
RECRUITING

Sofia, 1431, Bulgaria
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Vancouver, British Columbia, V5Z 1L7, Canada
Novartis Investigative Site
RECRUITING

Rimouski, Quebec, G5L 5T1, Canada
Novartis Investigative Site
RECRUITING

Valdivia, Los Ríos Region, 5110683, Chile
Novartis Investigative Site
RECRUITING

Santiago, RM, 7500588, Chile
Novartis Investigative Site
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Santiago, Santiago Metropolitan, 7500710, Chile
Novartis Investigative Site
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Guangzhou, Guangdong, 510080, China
Novartis Investigative Site
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Shantou, Guangdong, 515000, China
Novartis Investigative Site
RECRUITING

Nanjing, Jiangsu, 210008, China
Novartis Investigative Site
RECRUITING

Suzhou, Jiangsu, 215004, China
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Nanchang, Jiangxi, 330006, China
Novartis Investigative Site
RECRUITING

Pingxiang, Jiangxi, 337000, China
Novartis Investigative Site
RECRUITING

Changchun, Jilin, 130021, China
Novartis Investigative Site
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Linyi, Shandong, 276000, China
Novartis Investigative Site
RECRUITING

Chengdu, Sichuan, 610041, China
Novartis Investigative Site
RECRUITING

Ürümqi, Xinjiang, 830001, China
Novartis Investigative Site
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Ningbo, Zhejiang, 315016, China
Novartis Investigative Site
RECRUITING

Beijing, 100069, China
Novartis Investigative Site
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Beijing, 100730, China
Novartis Investigative Site
RECRUITING

Shanghai, 200127, China
Novartis Investigative Site
RECRUITING

Xinxiang, 453099, China
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Medellín, Antioquia, 050001, Colombia
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Barranquilla, Atlántico, 080020, Colombia
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Chía, Cundinamarca, 250001, Colombia
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Bucaramanga, Santander Department, 680003, Colombia
Novartis Investigative Site
RECRUITING

Cali, Valle del Cauca Department, 760046, Colombia
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Bogotá, 111211, Colombia
Novartis Investigative Site
RECRUITING

Brno, 638 00, Czechia
Novartis Investigative Site
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Prague, 128 00, Czechia
Novartis Investigative Site
RECRUITING

Uherské Hradiště, 686 01, Czechia
Novartis Investigative Site
RECRUITING

Montpellier, 34295, France
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Paris, 75013, France
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Paris, 75014, France
Novartis Investigative Site
RECRUITING

Toulouse, 31054, France
Novartis Investigative Site
RECRUITING

Toulouse, 31059, France
Novartis Investigative Site
WITHDRAWN

Cologne, North Rhine-Westphalia, 50937, Germany
Novartis Investigative Site
RECRUITING

Leipzig, Saxony, 04103, Germany
Novartis Investigative Site
RECRUITING

Guatemala City, 01010, Guatemala
Novartis Investigative Site
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Székesfehérvár, Fejér, 8000, Hungary
Novartis Investigative Site
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Gyula, 5700, Hungary
Novartis Investigative Site
RECRUITING

Zalaegerszeg, 8900, Hungary
Novartis Investigative Site
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Ahmedabad, Gujarat, 380006, India
Novartis Investigative Site
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Ahmedabad, Gujarat, 380015, India
Novartis Investigative Site
RECRUITING

Kozhikode, Kerala, 673008, India
Novartis Investigative Site
RECRUITING

Kolhāpur, Maharashtra, 416001, India
Novartis Investigative Site
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Nagpur, Maharashtra, 441108, India
Novartis Investigative Site
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Nashik, Maharashtra, 422101, India
Novartis Investigative Site
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Pune, Maharashtra, 411001, India
Novartis Investigative Site
RECRUITING

New Delhi, 110029, India
Novartis Investigative Site
RECRUITING

New Delhi, 110075, India
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Haifa, 3109601, Israel
Novartis Investigative Site
RECRUITING

Ramat Gan, 5265601, Israel
Novartis Investigative Site
RECRUITING

Pisa, PI, 56126, Italy
Novartis Investigative Site
RECRUITING

Torino, TO, 10128, Italy
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Nagoya, Aichi-ken, 4578510, Japan
Novartis Investigative Site
RECRUITING

Nagoya, Aichi-ken, 4578511, Japan
Novartis Investigative Site
RECRUITING

Sapporo, Hokkaido, 060-8648, Japan
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Yokohama, Kanagawa, 236-0004, Japan
Novartis Investigative Site
RECRUITING

Bunkyo-ku, Tokyo, 1138519, Japan
Novartis Investigative Site
RECRUITING

Chuo Ku, Tokyo, 104-8560, Japan
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Fuchū, Tokyo, 1838524, Japan
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Shinjuku-ku, Tokyo, 1608582, Japan
Novartis Investigative Site
RECRUITING

Ipoh, Perak, 30450, Malaysia
Novartis Investigative Site
RECRUITING

León, Guanajuato, 37160, Mexico
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Guadalajara, Jalisco, 44160, Mexico
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Mexico City, Mexico City, 06700, Mexico
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

Morelia, Michoacán, 58000, Mexico
Novartis Investigative Site
RECRUITING

Mérida, Yucatán, 97070, Mexico
Novartis Investigative Site
ACTIVE_NOT_RECRUITING

México, 07760, Mexico
Novartis Investigative Site
RECRUITING

Wroclaw, Lower Silesian Voivodeship, 52-210, Poland
Novartis Investigative Site
RECRUITING

Bydgoszcz, 85-065, Poland
Novartis Investigative Site
RECRUITING

Bydgoszcz, 85-168, Poland
Novartis Investigative Site
RECRUITING

Bytom, 41 902, Poland
Novartis Investigative Site
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Warsaw, 00-874, Poland
Novartis Investigative Site
RECRUITING

Warsaw, 04-141, Poland
Novartis Investigative Site
RECRUITING

Braga, 4710243, Portugal
Novartis Investigative Site
RECRUITING

Lisbon, 1050-034, Portugal
Novartis Investigative Site
RECRUITING

Cluj-Napoca, Cluj, 400006, Romania
Novartis Investigative Site
RECRUITING

Brasov, 500283, Romania
Novartis Investigative Site
RECRUITING

Bucharest, 011172, Romania
Novartis Investigative Site
RECRUITING

Košice, 040 01, Slovakia
Novartis Investigative Site
RECRUITING

Pretoria, Gauteng, 0002, South Africa
Novartis Investigative Site
RECRUITING

Cape Town, Western Cape, 7405, South Africa
Novartis Investigative Site
RECRUITING

Cape Town, Western Cape, 7500, South Africa
Novartis Investigative Site
RECRUITING

Somerset West, Western Cape, 7130, South Africa
Novartis Investigative Site
RECRUITING

Umhlanga, 4320, South Africa
Novartis Investigative Site
RECRUITING

Gwangju, 61469, South Korea
Novartis Investigative Site
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Seoul, 04763, South Korea
Novartis Investigative Site
RECRUITING

Seoul, 06591, South Korea
Novartis Investigative Site
RECRUITING

Santiago Compostela, A Coruna, 15706, Spain
Novartis Investigative Site
RECRUITING

Badalona, Barcelona, 08916, Spain
Novartis Investigative Site
RECRUITING

Santander, Cantabria, 39008, Spain
Novartis Investigative Site
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Barcelona, Catalonia, 08003, Spain
Novartis Investigative Site
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San Sebastian Reyes, Madrid, 28702, Spain
Novartis Investigative Site
RECRUITING

Barcelona, 08035, Spain
Novartis Investigative Site
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Madrid, 28034, Spain
Novartis Investigative Site
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Valencia, 46014, Spain
Novartis Investigative Site
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Kaohsiung City, 83301, Taiwan
Novartis Investigative Site
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Taichung, 40447, Taiwan
Novartis Investigative Site
RECRUITING

Taichung, 407219, Taiwan
Novartis Investigative Site
RECRUITING

Taipei, 11217, Taiwan
Novartis Investigative Site
RECRUITING

Taoyuan, 33305, Taiwan
Novartis Investigative Site
RECRUITING

Bangkok, 10400, Thailand
Novartis Investigative Site
RECRUITING

Bangkok, 10700, Thailand
Novel Research LLC
TERMINATED

Bellaire, Texas, 77401, United States
Paramount Med Rsrch and Consult LLC
RECRUITING

Middleburg Heights, Ohio, 44130, United States
Parris and Associates Rheumatology
RECRUITING

Lawrenceville, Georgia, 30044, United States
Pinnacle Research Group Llc
RECRUITING

Anniston, Alabama, 36207, United States
Providence Medical Center
RECRUITING

Burbank, California, 91505, United States
Robert A Hozman MD SC
RECRUITING

Skokie, Illinois, 60076, United States
Shelby Research LLC
RECRUITING

Memphis, Tennessee, 38121, United States
University Of Maryland
ACTIVE_NOT_RECRUITING

Baltimore, Maryland, 21201, United States
University of Colorado Denver
RECRUITING

Aurora, Colorado, 80045, United States
West Tennessee Research Institute
RECRUITING

Jackson, Tennessee, 38305, United States
Willow Rheumatology Wellness
RECRUITING

Willowbrook, Illinois, 60527, United States

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