New drug afimkibart tested for Long-Term arthritis control

NCT ID NCT07620392

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study is testing the long-term safety and effectiveness of a drug called afimkibart in people with moderate to severe rheumatoid arthritis. Participants have already taken afimkibart in a previous study and will continue taking it. The goal is to see if the drug remains safe and helps control arthritis symptoms over a longer period.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: afimkibart (a drug)
What this could lead to: If successful, this could show that afimkibart is a safe and effective long-term treatment option for people with moderate to severe rheumatoid arthritis who haven't responded well to other therapies.
What could go wrong: This is a Phase 2 extension study with only 120 participants, so results may not apply to everyone. Long-term side effects are still unknown, and the drug may not work as well over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RHEUMATOID ARTHRITIS

Contacts and locations

Locations

Accurate Clinical Management LLC
RECRUITING

Houston, Texas, 77089, United States
Centrum Kliniczno-Badawcze J. Brzezicki, B. Górnikiewicz-Brzezicka Lekarze Spó?ka Partne
RECRUITING

Elblag, 82-300, Poland
DM Clinical Research
RECRUITING

Tomball, Texas, 77375, United States
Reumatop Grzegorz Rozumek Karin Pistorius Spolka Jawna
RECRUITING

Wroclaw, 52-210, Poland
West Broward Rheumatology Associates, Inc.
RECRUITING

Tamarac, Florida, 33321, United States
Zespol Poradni Specjalistycznych REUMED filia nr 1 Wallenroda
RECRUITING

Lublin, 20-607, Poland

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