Hemophilia drug safety under the microscope: real-world study launched
NCT ID NCT04158934
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 207 people with hemophilia A who are already taking ADYNOVI/ADYNOVATE to prevent bleeding. Researchers want to see if any long-term side effects appear during normal use. The goal is to gather safety information, not to test if the drug works.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Azienda Ospedaliera Universitaria Policlinico Umberto I - Università di Roma La Sapienza
Roma, 00161, Italy
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Chang Gung Memorial Hospital, Linkou
Taoyuan, 333, Taiwan
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Clinical Hospital Sveti Duh
Zagreb, 10000, Croatia
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Debreceni Egyetem
Debrecen, 4032, Hungary
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Eszak-Pesti Centrumkorhaz - Honvedkorhaz
Budapest, 1134, Hungary
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Fakultni nemocnice v Motole
Prague, 150 06, Czechia
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Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico
Milan, 20122, Italy
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, 00168, Italy
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Heim Pal Orszagos Gyermekgyogyaszati Intezet
Budapest, 1089, Hungary
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Hospital Regional Universitario de Malaga
Málaga, 29010, Spain
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Hospital Universitari Son Espases
Palma de Mallorca, Balearic Islands, 07120, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitario La Paz
Madrid, 28046, Spain
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Hospital Universitario de Gran Canaria Dr. Negrin
Las Palmas, 35010, Spain
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King Chulalongkorn Memorial Hospital
Bangkok, 10330, Thailand
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Krajska zdravotni a.s. - Masarykova nemocnice v Usti nad Labem o.z.
Ústí nad Labem, 40113, Czechia
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Kyung Hee University Hospital at Gangdong
Seoul, 134-727, South Korea
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MacKay Memorial Hospital_Taipei Branch
Taipei, 10449, Taiwan
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Maharaj Nakorn Chiang Mai Hospital
Chiang Mai, 50200, Thailand
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Mohacsi Korhaz
Mohács, 7700, Hungary
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Pecsi Tudomanyegyetem Klinikai Kozpont
Pécs, 7624, Hungary
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Phramongkutklao Hospital
Bangkok, 10400, Thailand
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SHAT of Oncohaematology Diseases
Sofia, 1527, Bulgaria
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SRH Kurpfalzkrankenhaus Heidelberg GmbH
Heidelberg, Baden-Wurttemberg, D-69123, Germany
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Sahlgrenska Universitetssjukhuset
Gothenburg, 41345, Sweden
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Siriraj Hospital
Bangkoknoi Bangkok, 10700, Thailand
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Szabolcs-Szatmar-Bereg Varmegyei Oktatokorhaz
Nyíregyháza, 4400, Hungary
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Tri-Service General Hospital
Taipei, 11490, Taiwan
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UF Health Shands Hospital
Gainesville, Florida, 32610, United States
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Ulsan University Hospital
Ulsan, 44033, South Korea
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Universitaetsklinikum Bonn AoeR
Bonn, 53127, Germany
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University Medical Centre Groningen-UMCG
Groningen, 9713 GZ, Netherlands
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University hospital centre Zagreb
Zagreb, 10000, Croatia
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University hospital centre Zagreb
Zagreb, 1000, Croatia
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Vivantes Klinikum im Friedrichshain
Berlin, 10249, Germany
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Werlhof-Institut GmbH
Hanover, 30159, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A Once-a-Week shot could transform hemophilia Care—Even for those with inhibitors
- Can a new clotting factor offer better bleed protection for severe hemophilia?
- Do newer hemophilia drugs protect joints better? study aims to find out
- Newborn screening study aims to catch rare diseases at birth
- Could home blood tests transform hemophilia care? study seeks patient views
- New clotting factor shows promise for hemophilia a bleeds