Moderna tests Long-Term safety of rare disease treatment

NCT ID NCT05130437

Summary

This study follows people with propionic acidemia who were in an earlier trial of the experimental treatment mRNA-3927. It aims to check the long-term safety of continuing this treatment and see if it helps control the disease. About 50 participants will receive the same dose they were getting before and be monitored for side effects and hospital visits.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Birmingham Women's and Children's NHS Foundation Trust

    COMPLETED

    Birmingham, West Midlands, B4 6NH, United Kingdom

  • Duke University Medical System (Duke Health)

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Fujita Health University Hospital

    NOT_YET_RECRUITING

    Toyoake-shi, Akita, 470-1192, Japan

  • Great Ormond Street Hospital for Children NHS Foundation Trust

    RECRUITING

    London, WC1N 3JH, United Kingdom

  • Hospital For Sick Children

    RECRUITING

    Toronto, Ontario, M5G 1X8, Canada

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

  • Ronald Reagan UCLA Medical Center

    RECRUITING

    Los Angeles, California, 90095, United States

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

  • The Children's Hospital of Philadelphia (CHOP)

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • University Hospital Birmingham NHS Foundation Trust

    RECRUITING

    Birmingham, West Midlands, B15 2TH, United Kingdom

  • University of Michigan Hospitals

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • Willink Biochemical Genetics Unit - Manchester

    RECRUITING

    Manchester, England, M13 9WL, United Kingdom

Conditions

Explore the condition pages connected to this study.