Old Weight-Loss drug gets a second look for Long-Term use
NCT ID NCT05176626
First seen Apr 25, 2026 · Last updated May 15, 2026 · Updated 6 times
Summary
This study looks at whether the FDA-approved weight-loss drug phentermine can be used safely for up to 2 years to help people with obesity lose weight and improve health. About 870 adults with a BMI of 30 or higher (or 27 with weight-related health issues) will take the drug and be followed for 2 years. Researchers will measure weight loss, blood pressure changes, and other health effects to see if long-term use is a good option for managing obesity.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Atrium Health Wake Forest Baptist Weight Management Center
Winston-Salem, North Carolina, 27104, United States
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HealthPartners Institute
Saint Louis Park, Minnesota, 55416, United States
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Kaiser Permanente Southern California
Los Angeles, California, 90034, United States
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UT Center for Obesity Medicine and Metabolic Performance
Bellaire, Texas, 77401, United States
Conditions
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