10-Year PKU drug safety study launches to track immune reactions

NCT ID NCT06305234

First seen Apr 13, 2026 · Last updated May 03, 2026 · Updated 3 times

Summary

This study follows 200 people with PKU who are taking or about to start Palynziq (pegvaliase) for up to 10 years. Researchers will track immune responses, inflammation, and lab results to better understand long-term side effects like allergic reactions and joint pain. The goal is to gather safety data, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Children's Wisconsin/Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Riley Children's Hospital/ Indiana University Health

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Tulane University School of Medicine

    RECRUITING

    New Orleans, Louisiana, 70112, United States

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

  • University of Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

  • Vanderbilt University Medical School

    RECRUITING

    Nashville, Tennessee, 37235, United States

Conditions

Explore the condition pages connected to this study.