Cancer drug niraparib gets Long-Term safety check in extension trial
NCT ID NCT04641247
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study offers continued access to niraparib, a daily oral cancer drug, for up to 37 patients with ovarian or breast cancer who have already completed a prior niraparib trial and are still benefiting. The main goal is to monitor long-term safety, including side effects and changes in daily functioning. Participants will continue their current niraparib dose and be followed for any health issues.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Niraparib (a targeted cancer drug taken as a daily pill)
What this could lead to
If successful, this study could confirm that long-term niraparib is safe and continues to control ovarian or breast cancer, offering a maintenance treatment option.
What could go wrong
This is a small, open-label extension study (37 participants) focused on safety, not on proving the drug works better. It only includes people who already tolerated niraparib, so results may not apply to all patients. Side effects like fatigue, nausea, or blood issues remain possible.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Locations
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GSK Investigational Site
COMPLETEDTucson, Arizona, 85710, United States
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GSK Investigational Site
RECRUITINGEncinitas, California, 92024, United States
Contact
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GSK Investigational Site
RECRUITINGLos Angeles, California, 90048, United States
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GSK Investigational Site
COMPLETEDWhittier, California, 90603, United States
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GSK Investigational Site
COMPLETEDJacksonville, Florida, 32224, United States
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GSK Investigational Site
RECRUITINGAtlanta, Georgia, 30342, United States
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Contact
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GSK Investigational Site
RECRUITINGHarvey, Illinois, 60426, United States
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GSK Investigational Site
RECRUITINGBoston, Massachusetts, 02115, United States
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GSK Investigational Site
RECRUITINGGrand Rapids, Michigan, 60637-1470, United States
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GSK Investigational Site
RECRUITINGMorristown, New Jersey, 07962-1956, United States
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Contact
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GSK Investigational Site
RECRUITINGLake Success, New York, 11042, United States
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GSK Investigational Site
RECRUITINGCharlotte, North Carolina, 28204, United States
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GSK Investigational Site
COMPLETEDCleveland, Ohio, 44195, United States
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GSK Investigational Site
RECRUITINGGraz, A-8036, Austria
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Contact
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GSK Investigational Site
RECRUITINGVienna, 1090, Austria
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GSK Investigational Site
RECRUITINGKelowna, British Columbia, V5Z 4E6, Canada
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GSK Investigational Site
RECRUITINGToronto, Ontario, M5G 2M9, Canada
Contact
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GSK Investigational Site
RECRUITINGMontreal, Quebec, H4A 3J1, Canada
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GSK Investigational Site
COMPLETEDOdense C, 5000, Denmark
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GSK Investigational Site
COMPLETEDNantes, 44202, France
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GSK Investigational Site
COMPLETEDNice, 06189, France
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GSK Investigational Site
RECRUITINGHaifa, 3109601, Israel
Contact
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GSK Investigational Site
RECRUITINGCremona, 26100, Italy
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GSK Investigational Site
RECRUITINGMadrid, 28040, Spain
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GSK Investigational Site
RECRUITINGMadrid, 28046, Spain
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