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Can a tiny eye surgery keep glaucoma in check for years?

NCT ID NCT07780916

Knowledge-focused Sponsor: Wuerzburg University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 24, 2026 · Last updated Aug 26, 2026 · Updated 2 times

Summary

This study looks at how well a minimally invasive glaucoma surgery called ab-interno trabeculotomy (AIT) holds up over the long term. Researchers will review the medical records of 200 glaucoma patients who had the surgery between 2019 and 2021 and invite them for a single follow-up visit. At that visit, they will measure eye pressure, vision, and eye structure, and compare these to pre-surgery values. The goal is to see whether the surgery provides lasting pressure reduction and to help guide future patient selection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ab-interno trabeculotomy (AIT) using the Trabectome device, a minimally invasive glaucoma surgery
What this could lead to
If successful, this could help doctors better predict which glaucoma patients benefit most from this surgery and improve long-term treatment decisions.
What could go wrong
This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results depend on comparing past records with a single follow-up visit, and long-term outcomes may vary widely among patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with glaucoma who underwent ab-interno trabeculotomy (AIT) using the Trabectome device at the Department of Ophthalmology, University Hospital Würzburg, between 2019 and 2021. Patients were identified retrospectively through surgical records and invited for a single prospective follow-up visit in order of longest time elapsed since surgery, prioritizing those operated earliest within the inclusion period.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of glaucoma * Previous ab-interno trabeculotomy (AIT) using the Trabectome device performed at the Department of Ophthalmology, University Hospital Würzburg * Surgery performed between 2019 and 2021 * Ability to provide written informed consent * Age ≥ 18 years at time of surgery Exclusion Criteria: * Inability to attend the study visit * Withdrawal of informed consent * Insufficient medical records for pre-operative baseline data retrieval

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Conditions

The condition(s) this trial relates to.

glaucoma glaucoma 1, open angle, l

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Glaucoma Glaucoma 1, open angle, D (disorder) Glaucoma eye Glaucoma following surgery Glaucoma patient

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Hospital Würzburg

    RECRUITING

    Würzburg, Bavaria, 97080, Germany

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