Eczema drug dupilumab tested for Long-Term use in kids

NCT ID NCT02612454

Ongoing Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at the long-term safety of dupilumab (Dupixent) in children aged 6 months to 18 years with atopic dermatitis (eczema). About 880 kids who were in earlier dupilumab studies will continue treatment. Researchers will track side effects and check if a pre-filled pen works as well as a syringe. The goal is to see if the drug remains safe and effective over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dupilumab (Dupixent)

What this could lead to

If successful, this could confirm that dupilumab is safe and effective for long-term use in children with eczema, offering a reliable treatment option.

What could go wrong

This is an open-label extension study, meaning everyone knows they are getting the drug, which can bias results. Long-term side effects are still being monitored, and the study may not prove the drug works better than no treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

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Locations

Regeneron Investigational Site

Birmingham, Alabama, 35209, United States
Regeneron Investigational Site

Gilbert, Arizona, 85234, United States
Regeneron Investigational Site

Bakersfield, California, 93309, United States
Regeneron Investigational Site

Long Beach, California, 90808, United States
Regeneron Investigational Site

Los Angeles, California, 90027, United States
Regeneron Investigational Site

Orange, California, 92868, United States
Regeneron Investigational Site

Palo Alto, California, 92304, United States
Regeneron Investigational Site

Rolling Hills Estates, California, 90274, United States
Regeneron Investigational Site

San Diego, California, 92123, United States
Regeneron Investigational Site

Centennial, Colorado, 80112, United States
Regeneron Investigational Site

Washington D.C., District of Columbia, 20016, United States
Regeneron Investigational Site

Coral Gables, Florida, 33146, United States
Regeneron Investigational Site

Tampa, Florida, 33613, United States
Regeneron Investigational Site

Tampa, Florida, 33624, United States
Regeneron Investigational Site

Columbus, Georgia, 31904, United States
Regeneron Investigational Site

Macon, Georgia, 31217, United States
Regeneron Investigational Site

Sandy Springs, Georgia, 30328, United States
Regeneron Investigational Site

Chicago, Illinois, 60611, United States
Regeneron Investigational Site

Skokie, Illinois, 60077, United States
Regeneron Investigational Site

Rockville, Maryland, 20850, United States
Regeneron Investigational Site

Boston, Massachusetts, 02115, United States
Regeneron Investigational Site

Boston, Massachusetts, 02116, United States
Regeneron Investigational Site

Ypsilanti, Michigan, 48197, United States
Regeneron Investigational Site

Plymouth, Minnesota, 55441, United States
Regeneron Investigational Site

St Louis, Missouri, 63104, United States
Regeneron Investigational Site

Forest Hills, New York, 11375, United States
Regeneron Investigational Site

New York, New York, 10029, United States
Regeneron Investigational Site

Rochester, New York, 14642, United States
Regeneron Investigational Site

Gahanna, Ohio, 43230, United States
Regeneron Investigational Site

Portland, Oregon, 97239, United States
Regeneron Investigational Site

Charleston, South Carolina, 29425, United States
Regeneron Investigational Site

North Charleston, South Carolina, 29420, United States
Regeneron Investigational Site

Bellaire, Texas, 77401-3505, United States
Regeneron Investigational Site

Fort Worth, Texas, 76244, United States
Regeneron Investigational Site

San Antonio, Texas, 78218, United States
Regeneron Investigational Site

Norfolk, Virginia, 23502, United States
Regeneron Investigational Site

Seattle, Washington, 98105, United States
Regeneron Investigational Site

Calgary, Alberta, T2G 1B1, Canada
Regeneron Investigational Site

Surrey, British Columbia, V3R 6A7, Canada
Regeneron Investigational Site

Winnipeg, Manitoba, R3C 0N2, Canada
Regeneron Investigational Site

Markham, Ontario, L3P 1X2, Canada
Regeneron Investigational Site

Ottawa, Ontario, K2C 2N3, Canada
Regeneron Investigational Site

Peterborough, Ontario, K9J 5K2, Canada
Regeneron Investigational Site

Waterloo, Ontario, N2J 1C4, Canada
Regeneron Investigational Site

Windsor, Ontario, N8W 1E6, Canada
Regeneron Investigational Site

Montreal, Quebec, H3T 1C5, Canada
Regeneron Investigational Site

Kutná Hora, 28401, Czechia
Regeneron Investigational Site

Prague, 10034, Czechia
Regeneron Investigational Site

Ústí nad Labem, 40113, Czechia
Regeneron Investigational Site

Frankfurt am Main, Hesse, 60590, Germany
Regeneron Investigational Site

Münster, North Rhine-Westphal, 48149, Germany
Regeneron Investigational Site

Dresden, Saxony, 01307, Germany
Regeneron Investigational Site

Gera, 07548, Germany
Regeneron Investigational Site

Hamburg, 22149, Germany
Regeneron Investigational Site

Munich, 80337, Germany
Regeneron Investigational Site

Szolnok, Jász-Nagykun-Szolnok, 5000, Hungary
Regeneron Investigational Site

Kaposvár, 7400, Hungary
Regeneron Investigational Site

Miskolc, 3526, Hungary
Regeneron Investigational Site

Szeged, 6720, Hungary
Regeneron Investigational Site

Ostrowiec Świętokrzyski, Kielce, 27-400, Poland
Regeneron Investigational Site

Wroclaw, Lower Silesian Voivodeship, 50-381, Poland
Regeneron Investigational Site

Wroclaw, Lower Silesian Voivodeship, 50368, Poland
Regeneron Investigational Site

Krakow, Malopolska, 30 363, Poland
Regeneron Investigational Site

Krakow, Malopolska, 31-011, Poland
Regeneron Investigational Site

Katowice, Silesian Voivodeship, 40-648, Poland
Regeneron Investigational Site

Bialystok, 15 453, Poland
Regeneron Investigational Site

Bydgoszcz, 85-065, Poland
Regeneron Investigational Site

Chorzów, 41-500, Poland
Regeneron Investigational Site

Gdansk, 80-152, Poland
Regeneron Investigational Site

Katowice, 40 611, Poland
Regeneron Investigational Site

Krakow, 30 363, Poland
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Lodz, 90-265, Poland
Regeneron Investigational Site

Warsaw, 01-142, Poland
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Warsaw, 01-817, Poland
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Warsaw, 02-758, Poland
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Warsaw, 91-142, Poland
Regeneron Investigational Site

London, Greater London, SE1 7EH, United Kingdom
Regeneron Investigational Site

Manchester, Lancashire, M13 9WL, United Kingdom
Regeneron Investigational Site

Sheffield, South Yorkshire, S10 2TH, United Kingdom
Regeneron Investigational site

Mission Viejo, California, 92691, United States
Regeneron Investigational site

Plainfield, Indiana, 46168, United States
Regeneron Investigational site

Philadelphia, Pennsylvania, 19104, United States
Regeneron Study Site

Tübingen, Baden-Wurttemberg, 72076, Germany
Regeneron Study Site

München, 80802, Germany