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Can a home exercise program help long COVID patients take back control?

NCT ID NCT06822179

Symptom relief Sponsor: CEU San Pablo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Researchers are testing whether a 12-week online rehabilitation program helps people with long COVID manage their own health, fatigue, and quality of life. The program combines personalized exercise with education sessions and a mobile app for daily tracking. Participants attend weekly online sessions and use the app to log symptoms and progress. The trial compares this program with usual care to see if it improves self-management and energy levels.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A 12-week personalized telerehabilitation program combining guided exercise and self-management education, delivered online and through a mobile app
What this could lead to
If it works, this could offer a home-based way for people with long COVID to build confidence in managing their symptoms and improve daily energy and quality of life.
What could go wrong
The trial is small and early-stage, so results may not hold for everyone with long COVID. Exercise can also trigger symptom flare-ups in people with post-exertional malaise, and the program requires a smartphone and reliable internet access.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

57 people

The number who actually took part.

Started

Mar 2025

Finished

Sep 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Post COVID-19 condition: individuals with a history of probable or confirmed SARS-CoV-2 infection, usually 3 months from the onset of COVID-19 with symptoms that last for at least 2 months and cannot be explained by an alternative diagnosis. Common symptoms include fatigue, shortness of breath, cognitive dysfunction * Between 18 and 75 years of age * Possibility of access and use of smartphone. * Ability to attend the clinic in person for an initial session. Exclusion Criteria: * Patients with a history of respiratory or cardiovascular diseases prior to COVID-19, other acute or chronic diseases that may interfere with the study * Pregnancy/breastfeeding * Those with contraindications to respiratory muscle training.

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Conditions

The condition(s) this trial relates to.

COVID-19 long COVID-19 Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Long COVID syndrome

Contacts and locations

Locations

  • CEU San Pablo University

    Madrid, Madrid, 28003, Spain

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